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1

Binding to CD20 by Anti-B1 Antibody or F(ab')2is sufficient for induction of apoptosis in B-cell lines

Pina M. Cardarelli, Maire Quinn, Dana Buckman, Yu Fang, David Colcher, David J. King, Christopher Bebbington, Geoffrey Yarranton

Journal:

Cancer Immunology, Immunotherapy

Year:

2002

Language:

english

File:

PDF, 258 KB

english, 2002

2

Production of human monoclonal antibody in eggs of chimeric chickens

Zhu, Lei, van de Lavoir, Marie-Cecile, Albanese, Jenny, Beenhouwer, David O, Cardarelli, Pina M, Cuison, Severino, Deng, David F, Deshpande, Shrikant, Diamond, Jennifer H, Green, Lynae

Journal:

Nature Biotechnology

Year:

2005

Language:

english

File:

PDF, 454 KB

english, 2005

3

LPAM-1 (integrin α4β7)-ligand binding: overlapping binding sites recognizing VCAM-1, MAdCAM-1 and CS-1 are blocked by fibrinogen, a fibronectin-like polymer and RGD-like cyclic peptides

Yi Yang, Pina M. Cardarelli, Klaus Lehnert, Shelley Rowland, Geoffrey W. Krissansen

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 189 KB

english, 1998

4

Cytokine induction of monocyte chemoattractant protein-1 gene expression in human endothelial cells depends on the cooperative action of NF-χB and AP-1

Teresa Martin, Pina M. Cardarelli, Graham C. N. Parry, Katherine A. Felts, Ronald R. Cobb

Journal:

European Journal of Immunology

Year:

1997

Language:

english

File:

PDF, 907 KB

english, 1997

5

A β-turn mimic and a thiomethylene dipeptide surrogate employed in the study of cyclic peptide RGD and RCD cell-adhesion inhibitors

Gilbert M. Rishton, Nancy K. Harn, Stephan J. Cripps, Shiu-Lan Chiang, Christy Mikos, Pina Cardarelli, Thomas J. Lobl, Frank Gorcsan, Mary Moscinski, Nancy G. J. Delaet, Sharon M. Walker

Journal:

International Journal of Peptide Research and Therapeutics

Year:

1996

Language:

english

File:

PDF, 536 KB

english, 1996

6

A nonfucosylated human antibody to CD19 with potent B-cell depletive activity for therapy of B-cell malignancies

Pina M. Cardarelli, Chetana Rao-Naik, Sharline Chen, Haichun Huang, Amie Pham, Maria-Cristina Moldovan-Loomis, Chin Pan, Ben Preston, David Passmore, Jie Liu, Michelle R. Kuhne, Alison Witte, Diann Bl

Journal:

Cancer Immunology, Immunotherapy

Year:

2010

Language:

english

File:

PDF, 385 KB

english, 2010

7

Synthesis and SAR of N-Benzoyl-l-Biphenylalanine Derivatives: Discovery of TR-14035, A Dual α4β7/α4β1 Integrin Antagonist

Ila Sircar, Kristjan S Gudmundsson, Richard Martin, Jimmy Liang, Sumihiro Nomura, Honnappa Jayakumar, Bradley R Teegarden, Dawn M Nowlin, Pina M Cardarelli, Jason R Mah, Samuel Connell, Ronald C Griff

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 338 KB

english, 2002

8

Inhibition of Tyrosine Kinases Blocks Adhesion-Induced T-Cell Coactivation Without Interfering with T-Cell Adhesion to Endothelial Cell–Surface Ligands

Dawn M. Nowlin, Pina M. Cardarelli, Lynn Young, Jason Mah, Katherine A. Felts, Marian Mastrangelo, Ronald R. Cobb

Journal:

Year:

2002

Language:

english

File:

PDF, 956 KB

english, 2002

9

A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis

Michael Yellin, Igor Paliienko, Andra Balanescu, Semen Ter-Vartanian, Vira Tseluyko, Li-An Xu, Xiaolu Tao, Pina M. Cardarelli, Heidi LeBlanc, Geoff Nichol, Codrina Ancuta, Rodica Chirieac, Allison Luo

Journal:

Arthritis & Rheumatism

Year:

2012

Language:

english

File:

PDF, 199 KB

english, 2012

10

Fibronectin augments anti-CD3-mediated IL-2 receptor (CD25) expression on human peripheral blood lymphocytes

Pina M. Cardarelli, Shinsuke Yamagata, Wolfgang Scholz, Mary A. Moscinski, Edward L. Morgan

Journal:

Cellular Immunology

Year:

1991

Language:

english

File:

PDF, 999 KB

english, 1991

11

Reversal of opsonic deficiency in surgical, trauma, and burn patients by infusion of purified human plasma fibronectin. Correlation with experimental observations

Thomas M. Saba, Frank A. Blumenstock, Dhiraj M. Shah, Ricardo H. Landaburu, Michael E. Hrinda, D.Curtis Deno, John M. Holman Jr., Eshin Cho, Claire Dayton, Pina M. Cardarelli

Journal:

The American Journal of Medicine

Year:

1986

Language:

english

File:

PDF, 1.38 MB

english, 1986

12

Mapping of MCP-1 functional domains by peptide analysis and site-directed mutagenesis

Susan A Steitz, Ko Hasegawa, Shiu-Lan Chiang, Ronald R Cobb, Mary A Castro, Thomas J Lobl, Masaki Yamada, Elias Lazarides, Pina M Cardarelli

Journal:

Year:

1998

Language:

english

File:

PDF, 228 KB

english, 1998

13

704 A Phase 1 Open-Label, Single-Dose, Dose-Escalation Study of Mdx-1100, a High-Affinity, Neutralizing, Fully Human Igg1κ Anti-CXCL10 (Ip10) Monoclonal Antibody, in Ulcerative Colitis

Robert Hardi, Lloyd Mayer, Stephan R. Targan, Michael Yellin, Pina M. Cardarelli, Kiron M. Das

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 185 KB

english, 2008

14

Antibody–drug conjugates: current status and future directions

Perez, Heidi L., Cardarelli, Pina M., Deshpande, Shrikant, Gangwar, Sanjeev, Schroeder, Gretchen M., Vite, Gregory D., Borzilleri, Robert M.

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 876 KB

english, 2014

15

T1145 A Double-Blind, Placebo-Controlled, Dose-Escalation, Safety and Pharmacokinetic Study of MDX-1100, a Fully Human Anti-CXCL10 Monoclonal Antibody, in Healthy Subjects

Yellin, Michael, Goldwater, Ronald, Blanset, Diann L., Cardarelli, Pina M.

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 167 KB

english, 2008

16

W1170 CXCL10 Expression and Biological Activities in Inflammatory Bowel Disease

Witte, Alison, Kuhne, Michelle R., Preston, Benjamin T., Wallace, Steven R., Chen, Sharline, Vasudevan, Geetha, Yellin, Michael, Das, Kiron M., Cardarelli, Pina M.

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 122 KB

english, 2008

17

T-Lymphocyte Differentiation and the Extracellular Matrix: Identification of a Thymocyte Subset That Attaches Specifically to Fibronectin

Pina M. Cardarelli and Michael D. Pierschbacher

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 947 KB

english, 1986

18

Identification of Fibronectin Receptors on T Lymphocytes

Pina M. Cardarelli and Michael D. Pierschbacher

Journal:

The Journal of Cell Biology

Year:

1987

Language:

english

File:

PDF, 2.14 MB

english, 1987

19

Preferential Expression of Fibronectin Receptors on Immature Thymocytes

Pina M. Cardarelli, I. Nicholas Crispe and Michael D. Pierschbacher

Journal:

The Journal of Cell Biology

Year:

1988

Language:

english

File:

PDF, 1.65 MB

english, 1988

20

The Receptor for Type I IFNs Is Highly Expressed on Peripheral Blood B Cells and Monocytes and Mediates a Distinct Profile of Differentiation and Activation of These Cells

Pogue, Sarah L., Preston, Benjamin T., Stalder, Joseph, Bebbington, Christopher R., Cardarelli, Pina M.

Journal:

Journal of Interferon & Cytokine Research

Year:

2004

Language:

english

File:

PDF, 515 KB

english, 2004

21

Novel detection of DNA-alkylated adducts of antibody–drug conjugates with potentially unique preclinical and biomarker applications

Thevanayagam, Lourdes, Bell, Alasdair, Chakraborty, Indrani, Sufi, Bilal, Gangwar, Sanjeev, Zang, Allen, Rangan, Vangipuram, Rao, Chetana, Wang, Zemin, Pan, Chin, Chong, Coling, Cardarelli, Pina, Desh

Journal:

Year:

2013

Language:

english

File:

PDF, 810 KB

english, 2013

22

First-in-human multicenter phase I study of BMS-936561 (MDX-1203), an antibody-drug conjugate targeting CD70

Owonikoko, Taofeek Kunle, Hussain, Arif, Stadler, Walter Michael, Smith, David C., Kluger, Harriet, Molina, Ana M., Gulati, Parul, Shah, Aadhar, Ahlers, Christoph Matthias, Cardarelli, Pina M., Cohen,

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 413 KB

english, 2016

23

High-Affinity Binding of Fibronectin to Cultured Kupffer Cells

Cardarelli, Pina M., Blumenstock, Frank A., McKeown-Longo, Paula J., Saba, Thomas M., Mazurkiewicz, Joseph E., Dias, James A.

Journal:

Journal of Leukocyte Biology

Year:

1990

Language:

english

File:

PDF, 1.99 MB

english, 1990

24

Soluble vascular cell adhesion molecule (VCAM)-Fc fusion protein induces leukotriene C 4 secretion in platelet-activating factor-stimulated eosinophils

Tsuruta, Ryosuke, Cobb, Ronald R., Mastrangelo, Marian, Lazarides, Elias, Cardarelli, Pina M.

Journal:

Journal of Leukocyte Biology

Year:

1999

Language:

english

File:

PDF, 98 KB

english, 1999

25

Fibronectin-Enhanced Attachment of Gelatin-Coated Erythrocytes to Isolated Hepatic Kupffer Cells

Cardarelli, Pina M., Blumenstock, Frank A., Saba, Thomas M., Rourke, F. James

Journal:

Journal of Leukocyte Biology

Year:

1984

Language:

english

File:

PDF, 1.62 MB

english, 1984

26

Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology

Selby, Mark J., Engelhardt, John J., Johnston, Robert J., Lu, Li-Sheng, Han, Minhua, Thudium, Kent, Yao, Dapeng, Quigley, Michael, Valle, Jose, Wang, Changyu, Chen, Bing, Cardarelli, Pina M., Blanset,

Journal:

Year:

2016

Language:

english

File:

PDF, 3.74 MB

english, 2016

27

Correction: Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology

Selby, Mark J., Engelhardt, John J., Johnston, Robert J., Lu, Li-Sheng, Han, Minhua, Thudium, Kent, Yao, Dapeng, Quigley, Michael, Valle, Jose, Wang, Changyu, Chen, Bing, Cardarelli, Pina M., Blanset,

Journal:

Year:

2016

Language:

english

File:

PDF, 1023 KB

english, 2016

28

Combination anti-CXCR4 and anti-PD-1 immunotherapy provides survival benefit in glioblastoma through immune cell modulation of tumor microenvironment

Wu, Adela, Maxwell, Russell, Xia, Yuanxuan, Cardarelli, Pina, Oyasu, Miho, Belcaid, Zineb, Kim, Eileen, Hung, Alice, Luksik, Andrew S., Garzon-Muvdi, Tomas, Jackson, Christopher M., Mathios, Dimitrios

Journal:

Journal of Neuro-Oncology

Year:

2019

Language:

english

File:

PDF, 1.88 MB

english, 2019

29

Soluble VCAM-1 binding to Î±4 integrins is cell-type specific and activation dependent and is disrupted during apoptosis in T cells

Rose, David M., Cardarelli, Pina M., Cobb, Ronald R., Ginsberg, Mark H.

Journal:

Year:

2000

File:

PDF, 319 KB

2000

30

A NOVEL SEMIâMECHANISTIC TUMOR GROWTH FRACTION MODEL FOR TRANSLATION OF PRECLINICAL EFFICACY OF ANTIâGLYPICAN 3 ANTIBODY DRUG CONJUGATE TO HUMAN

Singh, Renu, Kozhich, Alexander, Pan, Chin, Lee, Francis, Cardarelli, Pina, Rangan, Vangipuram, Iyer, Rama, Marathe, Punit

Journal:

Biopharmaceutics & Drug Disposition

Year:

2020

File:

PDF, 1.39 MB

2020